Direct flights to the Italian city will launch on 12 April.
More than a thousand islanders voted as part of Aurigny's destination survey.
Every Saturday for a month, holidaymakers can fly direct between Guernsey and Genoa.
Chief Commercial Officer at Aurigny, Sudeep Ghai, says the city has much to offer.
'Genoa offers a mix of culture, food, and sun, just in time for Easter.
'We’ve carefully crafted our seasonal schedule this year to offer our community direct connectivity to exciting destinations across Europe while continuing to safeguard the vital lifeline services to the UK that our customers rely on.'
Flights run until 10 May and start from £149.99 one way.
Channel Islands Contemporary Art Show opens
Alderney flights disrupted for six days
Main road to Guernsey's West coast to close for four months
Channel Island ferry service hopes to double passenger numbers in 2026
Extra Aurigny ATR lands in Guernsey
Guernsey charity to open a shop at Oatlands
Smartphone survey for Guernsey schools
Food waste prevention app launching in Guernsey
